Researchers In Japan Show That An Oral Dietary Supplement Similar To LONGEVINEX ADVANTAGE™ Improves Mobility

A combination glucosamine/chondroitin/quercetin oral supplement has been shown to improve mobility among adults in Japan over a 3- month period. The dietary supplement formula used in Japan is similar to LONGEVINEX ADVANTAGE™.

The formula used in Japan employed glucosamine and chondroitin to stimulate production of hyaluronan, the viscous lubricating agent in joint spaces. Quercetin was used as an anti-inflammatory agent. Longevinex Advantage™ employs oral hyaluronan itself as a stimulant for fibroblast cells in joint spaces to regenerate hyaluronan production. Oral hyaluronan is known to produce faster results and has now been shown to be orally absorbed. Longevinex Advantage™ also provides an array of natural small-molecules (resveratrol, quercetin, ferulic acid, green tea extract, grape seed extract, rice bran IP6) to both calm inflammation and inhibit hyaluronidase, the enzyme that breaks down hyaluronan.

Patients were in their sixties and experienced improvements in ability to walk and climb up and down stairs which was correlated with increased viscosity of joint fluid. The dietary supplement was used with reported side effects but was not effective for individuals with rheumatoid arthritis. The more common wear-and-tear osteoarthritic patients experienced dramatic improvement and a reduction in pain. [Bioscience, Biotechnology, Biochemistry 73: 288-92, 2009]