While scientists believe they are on the frontier of discovering technologies that will produce super longevity, the curse of living ...Posted: 05/11/2009
Americans can expect to live longer than their forefathers. But there is one curse of longevity that the mirror reveals - we all look old.Posted: 05/11/2009
Based upon a study of twins in their 70s, investigators report that the younger-looking twin will live significantly longer ...Posted: 12/18/2009
Hyaluronan (HA), a component found in Longevinex Advantage™, is likely to prolong the half-life of resveratrol and ...Posted: 05/20/2009
Red wine may be much more potent than was thought in extending human lifespan, researchers say in a new report that ...Posted: 06/04/2008
Recent studies suggesting a substance in red wine could be a possible anti-aging elixir have sparked a surge in sales ...Posted: 12/05/2006
How to live 100 years without growing old
Americans are living longer and starting to take anti-aging pills. But "how old will you appear when you are 82, or 102, or 122?"
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In 2008 leading university-based researchers put Longevinex® to the test when they placed laboratory mice on (a) a limited calorie diet, known to double the lifespan of many forms of life; (b) resveratrol-supplemented diet and (c) a Longevinex®- supplemented diet over a 3-month period.
At the end of the trial period, heart tissue from these animals was obtained and analyzed for protein content that determines gene activity. When genes make proteins this is called gene expression and when they cease making proteins this is called gene silencing.
Mice have ~25,000 genes, about the same number as humans, and these genes are similar in length and position as genes in the human genome (library of genes).
The gene analysis revealed that short-term calorie restriction altered 198 genes over the 3-month period. Plain resveratrol altered about the same number of genes, 225. Longevinex® altered 1711 genes, 9-fold more than plain resveratrol.
If these laboratory mice were to continue on a limited-calorie diet over their 3-year lifetime, 831 genes would be significantly altered (see chart).
This suggests that it would take continued life-long use of resveratrol to mimic the full genomic effect produced by a limited calorie diet, an effect which only took 12 weeks to activate with Longevinex®. Longevinex® switched 677 of 831 longevity genes (85%) in the same direction (switched on or off) as a calorie-restricted diet.
This is the closest any commercially available product has come to replicating the genetic effect of calorie restriction.
Activated 198 genes over 12 week period of time.
Activated 831 genes over entire life time
Activated 226 genes over 12 week period of time
Activated 1711 genes over 12 week period time